WM is a cancer of the lymphatic system which occurs in a type of white blood cell called a B-lymphocyte or B-cell. B-cells normally mature into plasma cells - whose job is to manufacture immunoglobulins (antibodies) to help the body fight infection. In WM, there is a malignant change to the B-cell in the late stages of maturing, and it continues to proliferate into a clone of identical cells, primarily in the bone marrow but also in the lymph nodes and other tissues and organs of the lymphatic system. These clonal cells over-produce an antibody of a specific class called Immunoglobulin M (IgM).

You can find the subtype review on Waldenström’s Macroglobulinemia here.

 

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The information on this website is for general use only. Please consult your physician if you think you may have lymphoma or require more detailed information on the best course of treatment for you.