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Health Technology Assessment

2025 HTA SIG Workshop

Amsterdam, The Netherlands

Building on the insights from the 2024 HTA SIG Workshop, Lymphoma Coalition hosted the 2025 session in Amsterdam on 6 October 2025, bringing together representatives from 13 countries: Belgium, Brazil, Canada, China, Denmark, France, Hong Kong, Ireland, Japan, Portugal, New Zealand, the Netherlands, and the United Kingdom.

This year’s workshop continued to strengthen Member engagement in health technology assessment by fostering shared learning, practical skill-building, and deeper exploration of emerging HTA trends.

The evolving role of artificial intelligence in HTA
Use of the PICO framework to develop patient-centred evidence questions
Considerations for advanced therapies such as CAR-T and bispecifics
The growing importance of real-world data and real-world evidence

The workshop also provided a space for Members to compare country contexts, exchange best practices, and identify common challenges and opportunities in advocating for equitable access to lymphoma and CLL treatments.

2024 HTA SIG Workshop

Rome, Italy

Health Technology Assessment Special Interest Group

In October 2024, Lymphoma Coalition (LC) hosted an afternoon workshop for Members of the Health Technology Assessment Special Interest Group (HTA SIG) in Rome, Italy. The 2024 workshop was attended by HTA SIG Members from 13 countries, namely: Australia, Belgium, Canada, China, Denmark, France, Hong Kong, Ireland, Israel, Japan, Portugal, The Netherlands and Slovakia.

A deep discussion on how to conduct a research analysis to help determine what constitutes good research, how to interpret complex data used in research articles, what patients and patient organisations might need to better understand research findings, and the need to better understand research specific terminology and language used in most studies.
A comparative case study of HTA appraisals and processes to better understand how different countries approach HTA and the variances in factors such as treatment comparisons, cost comparators, reimbursements and pricing models, transparent reporting, as well as country specific variables in financing.
The increased use of real-world data (RWD) and real-world evidence (RWE) in HTA recommendations across countries, how different countries are leveraging RWD/RWE in HTA in addition to some related factors such as data quality, methods for data collection and reporting, and the application of RWD/RWE data to support decision-making.
The risks, benefits and opportunities that artificial intelligence (AI) might present in relation to HTA, and what the future might hold if/when AI methods or practices are introduced into HTA processes.

During the 2024 HTA SIG Workshop, we learned:

HTA SIG Workshop learning outcomes

Health Technology Assessment: Similarities and Differences in Mechanisms, Systems and Processes across 27 Countries

Health Technology Assessment report preview

In the lymphoma treatment landscape, new therapies and emerging biotherapeutic products are transforming cancer care and treatment. Health technology assessment (HTA) systems for medicines and other health technologies differs across countries and regions.

Patient involvement in HTA helps to ensure the patients' perspective on the value of technologies is considered however, patient organisations are often resource constrained. Patient organisations are often expected to collect and incorporate evidence for HTA submissions that best reflects their respective patient community, including patient experiences and unmet needs. This data is not usually readily available and there is an added cost in securing it in a validated, credible manner. Additionally, the collection and analysis of data involves a unique skillset that may not be available in the local patient organisation.

Involving health care professionals and scientific societies in HTA processes is key as they bring valuable expertise and insights on the impact of health technologies. In many countries, scientific societies are engaged in the HTA process to provide input to assessments and reporting, as well as contribute to public health information and the evaluation of the impact of health technologies on care pathways.

Rare diseases affect millions of people worldwide. There are more than 80 different indolent and aggressive lymphoma subtypes, each with different diagnostic evaluation, treatment protocols, characteristics, indications, sub-populations, and outcomes. Many countries have prioritised rare diseases in their national health agendas or rare disease plans to address the unmet needs of patients in the rare disease space and promote research, improve access, and increase awareness.

The report, Health Technology Assessment Similarities and Differences in Mechanisms, Systems and Processes across 27 Countries is available for download in both A4 and letter size file format. To learn more about specific terms or definitions used broadly within the reports, please refer to the HTA glossary.

HTA Submissions

This form is for Lymphoma Coalition Members to submit Health Technology Assessment (HTA) materials as part of a shared repository of Member-led work.

The purpose of this repository is to support knowledge sharing by providing practical examples of how Members engage in HTA. These submissions can help inform future approaches, strengthen advocacy efforts, enhance patient involvement in HTA, and support more effective engagement with decision-makers.

Submissions should relate to your organisation’s experience engaging with HTA systems and processes at the national or regional level, including the medicine, therapy, or intervention under review.

To complete your submission, you are required to upload supporting HTA documents below. Submissions can be shared in your preferred language.

All submissions will be made available to Members to view through the Member Portal .

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